SGLT2 inhibitors and GLP-1 / GIP agonists (incl. weight-loss use) — what to do before elective surgery.
Draft — not yet clinically verified. Based on El-Boghdadly et al, Anaesthesia 2025 —
multidisciplinary consensus (Assoc. Anaesthetists / ABCD / BOMSS / CPOC / JBDS / RCoA / SOBA / UKCPA),
Boxes 1 & 2. Applies to elective care. Evidence is evolving; use shared decision-making and local policy.
Indication (diabetes vs weight loss vs heart failure/CKD) doesn't change the drug rule — the same applies to all.
e.g. pre-bariatric diet or prolonged bowel prep — extends the cessation window.
El-Boghdadly K, et al. Elective peri-operative management of adults taking GLP-1 receptor agonists,
GIP agonists and SGLT2 inhibitors: a multidisciplinary consensus statement. Anaesthesia 2025; doi:10.1111/anae.16541 (Boxes 1 & 2).
Source: El-Boghdadly et al, Anaesthesia 2025 (anae.16541). GLP-1/GIP → continue with
aspiration mitigation; SGLT2 → omit day before & day of surgery.
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